Internal Medicine

Download e-book for iPad: Angiotensin and the Heart by Gerd Heusch,H. Grobecker,B.E. Strauer

By Gerd Heusch,H. Grobecker,B.E. Strauer

within the final decade, ACE inhibitors became a cornerstone of cardiovascular drug treatment. precious results in sufferers with high blood pressure, center failure, and submit myocardial infarction were verified in huge scientific trials. In parallel, ex perimental learn has shifted the curiosity from the speedy homeostatic functionality of the circulating renin-angiotensin-system to the a number of paracrine services of neighborhood tissue renin-angiotensin-systems, together with hypertrophy, hyperplasia, athe- oenesis, and vasomotion. . It used to be the purpose or a symposium held in Hamburg, October 22-24, 1992, to compile a world panel of experimental and medical scientists and to debate the newest findings at the position of angiotensin and linked mediators in vehicle diovascular model and affliction, with a specific emphasis at the remedy of such illness by means of ACE inhibitors. The assembly and this e-book have been generously supported via Astra chemical substances. H. Grobecker G. Heusch B. E. Strauer Contents Foreword. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . V advent neighborhood expression and pathophysiological function of renin-angiotensin within the blood vessels and center Dzau, V. J. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Myocardial Perfusion Angiotensin, ACE-inhibitors and endothelial keep watch over of vasomotor tone Luscher, T. F. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 15 neighborhood and neurohumoral keep an eye on of coronary blood circulation Krajcar, M., G. Heusch. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 25 ACE-inhibitors in coronary artery illness? Vogt, M., W. Matz, B. E. Strauer . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . forty three Myocardial Hypertrophy Molecular mechanisms of cardiac gene expression Nadal-Ginard, B., V. Mahdavi . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . sixty five Myocardial perfusion based and self sufficient mechanisms of neighborhood myocardial disorder in hypertrophy Vatner, S. F., L. Hittinger . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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Angiotensin and the Heart by Gerd Heusch,H. Grobecker,B.E. Strauer


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